Human CHCHD3 protein (Recombinant) (N-His) (STJP007497)

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STJP007497
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CHCHD3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CHCHD3
Gene ID: 54927
Uniprot ID: MIC19_HUMAN
Immunogen Region: Ser58-Gly227
Immunogen: Homo sapiens (Human)
Function Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription.
Protein Name Micos Complex Subunit Mic19
Coiled-Coil-Helix-Coiled-Coil-Helix Domain-Containing Protein 3
Database Links Reactome: R-HSA-1268020
Reactome: R-HSA-8949613
Cellular Localisation Mitochondrion Inner Membrane
Lipid-Anchor
Intermembrane Side
Cytoplasm
Nucleus
Mitochondrion
Alternative Protein Names Micos Complex Subunit Mic19 protein
Coiled-Coil-Helix-Coiled-Coil-Helix Domain-Containing Protein 3 protein
CHCHD3 protein
MIC19 protein
MINOS3 protein

Information sourced from Uniprot.org

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