Human AGTR1 (Angiotensin II Receptor 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013381)

Human AGTR1 (Angiotensin II Receptor 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013381)

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STJE0013381
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.055ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This AGTR1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: AGTR1
Gene ID: 185
Uniprot ID: AGTR1_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Liver, lung, adrenal and adrenocortical adenomas.
Post Translational Modifications C-terminal Ser or Thr residues may be phosphorylated.
Function Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C. (Microbial infection) During SARS coronavirus-2/SARS-CoV-2 infection, it is able to recognize and internalize the complex formed by secreted ACE2 and SARS-CoV-2 spike protein through DNM2/dynamin 2-dependent endocytosis.
Protein Name Type-1 Angiotensin Ii Receptor
At1ar
At1br
Angiotensin Ii Type-1 Receptor
At1 Receptor
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-416476
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative ELISA Names Type-1 Angiotensin Ii Receptor ELISA kit
At1ar ELISA kit
At1br ELISA kit
Angiotensin Ii Type-1 Receptor ELISA kit
At1 Receptor ELISA kit
AGTR1 ELISA kit
AGTR1A ELISA kit
AGTR1B ELISA kit
AT2R1 ELISA kit
AT2R1B ELISA kit
output

Information sourced from Uniprot.org

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