• Human a2M (Alpha-2-Macroglobulin) Sandwich ELISA Kit (STJE0006794)

Human a2M (Alpha-2-Macroglobulin) Sandwich ELISA Kit (STJE0006794)

SKU:
STJE0006794

Shipping:
Free Shipping
Current Stock:
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.37ng/mL
Detection Limit: 0.781-50ng/mL
Short Description: This a2M Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: A2M
Gene ID: 2
Uniprot ID: A2MG_HUMAN
Sample Type: serum, plasma, urine or other biological fluids.
Tissue Specificity Secreted in plasma.
Post Translational Modifications
Function Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region, a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
Protein Name Alpha-2-Macroglobulin
Alpha-2-M
C3 And Pzp-Like Alpha-2-Macroglobulin Domain-Containing Protein 5
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-140837
Reactome: R-HSA-1474228
Reactome: R-HSA-8963896
Cellular Localisation Secreted
Alternative ELISA Names Alpha-2-Macroglobulin ELISA kit
Alpha-2-M ELISA kit
C3 And Pzp-Like Alpha-2-Macroglobulin Domain-Containing Protein 5 ELISA kit
A2M ELISA kit
CPAMD5 ELISA kit
FWP007 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance