| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-FAM20A-protein was developed from rabbit. For use in research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S4947RM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:2000-1:20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FAM20A |
| Gene ID: |
54757 |
| Uniprot ID: |
FA20A_HUMAN |
| Immunogen Region: |
500-600 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 500-600 of human FAM20A (NP_060035.2). |
| Immunogen Sequence: |
AIFDFLIGNMDRHHYEMFTK FGDDGFLIHLDNARGFGRHS HDEISILSPLSQCCMIKKKT LLHLQLLAQADYRLSDVMRE SLLEDQLSPVLTEPHLLALD R |
| Tissue Specificity | Highly expressed in lung and liver. Intermediate levels in thymus and ovary. |
| Post Translational Modifications | N-glycosylated. |
| Function | Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the 'matrix' that guides the deposition of the enamel minerals. |
| Protein Name | Pseudokinase Fam20a |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | SecretedGolgi ApparatusEndoplasmic Reticulum |
| Alternative Protein Names | Pseudokinase Fam20a proteinFAM20A proteinUNQ9388 proteinPRO34279 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
