Anti-ZNF423 antibody [N328B/37R] (STJA0019039)

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STJA0019039
£378.50 - £1,632.50
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Host: Mouse
Applications: ICC/IHC/WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Zinc Finger Protein 423 is suitable for use in Immunocytochemistry, Immunohistochemistry and Western Blot research applications.
Clonality : Monoclonal
Clone ID : N328B/37R
Conjugation: Unconjugated
Isotype: IgG1
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1.13 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: Znf423
Gene ID: 94187
Uniprot ID: ZN423_MOUSE
Function Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation.this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.
Protein Name Zinc Finger Protein 423
Early B-Cell Factor-Associated Zinc Finger Protein
Olf1/Ebf-Associated Zinc Finger Protein
Smad- And Olf-Interacting Zinc Finger Protein
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Zinc Finger Protein 423 antibody
Anti-Early B-Cell Factor-Associated Zinc Finger Protein antibody
Anti-Olf1/Ebf-Associated Zinc Finger Protein antibody
Anti-Smad- And Olf-Interacting Zinc Finger Protein antibody
Anti-Znf423 antibody
Anti-Ebfaz antibody
Anti-Kiaa0760 antibody
Anti-Nur12 antibody
Anti-Oaz antibody
Anti-Zfp423 antibody

Information sourced from Uniprot.org