• Immunohistochemistry analysis of paraffin-embedded rat kidney using WRB Rabbit polyclonal antibody (STJ29080) at dilution of 1:200 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.

Anti-WRB antibody (30-100) (STJ29080)

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STJ29080

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Host: Rabbit
Applications: WB/IHC
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-WRB (30-100) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GET1
Gene ID: 7485
Uniprot ID: GET1_HUMAN
Immunogen Region: 30-100
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-100 of human WRB (NP_004618.2).
Immunogen Sequence: SFSSFMSRVLQKDAEQESQM RAEIQDMKQELSTVNMMDEF ARYARLERKINKMTDKLKTH VKARTAQLAKI
Function Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum (ER). Together with CAMLG/GET2, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required to ensure correct topology and ER insertion of CAMLG.
Protein Name Guided Entry Of Tail-Anchored Proteins Factor 1
Congenital Heart Disease 5 Protein
Tail-Anchored Protein Insertion Receptor Wrb
Tryptophan-Rich Basic Protein
Database Links Reactome: R-HSA-9609523
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Guided Entry Of Tail-Anchored Proteins Factor 1 antibody
Anti-Congenital Heart Disease 5 Protein antibody
Anti-Tail-Anchored Protein Insertion Receptor Wrb antibody
Anti-Tryptophan-Rich Basic Protein antibody
Anti-GET1 antibody
Anti-CHD5 antibody
Anti-WRB antibody

Information sourced from Uniprot.org