• Western blot analysis of various lysates using USP6NL Rabbit polyclonal antibody (STJ118208) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-USP6NL antibody (300-600) (STJ118208)

SKU:
STJ118208

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-USP6NL (300-600) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: USP6NL
Gene ID: 9712
Uniprot ID: US6NL_HUMAN
Immunogen Region: 300-600
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human USP6NL (NP_055503.1).
Immunogen Sequence: SYTILKLHKKHLMKLSMEEL VEFFQETLAKDFFFEDDFVI EQLQISMTELKRAKLDLPEP GKEDEYPKKPLGQLPPELQS WGVHHLSNGQRSVGRPSPLA SGRRESGAPHRRHEHSPHPQ SRTGTPERAQPPRRKSVEEE SKKLKDEADFQRKLPSGPQD SSRQYNHAAANQNSNATSNI RKEFVPKWNKPSDVSATERT AKYTMEGKGRAAHPALAVTV PGPAEVRVSNVRPKMKALD
Tissue Specificity Widely expressed.
Function Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.
Protein Name Usp6 N-Terminal-Like Protein
Related To The N-Terminus Of Tre
Rn-Tre
Database Links Reactome: R-HSA-6811440
Cellular Localisation Golgi Apparatus
Cytoplasmic Vesicle
Alternative Antibody Names Anti-Usp6 N-Terminal-Like Protein antibody
Anti-Related To The N-Terminus Of Tre antibody
Anti-Rn-Tre antibody
Anti-USP6NL antibody
Anti-KIAA0019 antibody

Information sourced from Uniprot.org

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