| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-UGT2B4 (280-480) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
UGT2B4 |
| Gene ID: |
7363 |
| Uniprot ID: |
UD2B4_HUMAN |
| Immunogen Region: |
280-480 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 280-480 of human UGT2B4 (NP_066962.2). |
| Immunogen Sequence: |
LHCKPAKPLPKEMEEFVQSS GENGVVVFSLGSMVSNTSEE RANVIASALAKIPQKVLWRF DGNKPDTLGLNTRLYKWIPQ NDLLGHPKTRAFITHGGANG IYEAIYHGIPMVGVPLFADQ PDNIAHMKAKGAAVSLDFHT MSSTDLLNALKTVINDPLYK ENAMKLSRIHHDQPVKPLDR AVFWIEFVMRHKGAKHLRVA A |
| Function | UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile. Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds. Catalyzes the glucuronidation of the endogenous estrogen hormones such as estradiol and estriol. |
| Protein Name | Udp-Glucuronosyltransferase 2b4Udpgt 2b4Ugt2b4Hlug25Hyodeoxycholic Acid-Specific UdpgtUdpgth-1 |
| Database Links | Reactome: R-HSA-156588Reactome: R-HSA-9749641 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Udp-Glucuronosyltransferase 2b4 antibodyAnti-Udpgt 2b4 antibodyAnti-Ugt2b4 antibodyAnti-Hlug25 antibodyAnti-Hyodeoxycholic Acid-Specific Udpgt antibodyAnti-Udpgth-1 antibodyAnti-UGT2B4 antibodyAnti-UGT2B11 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
