| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TSPYL5 (201-383) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TSPYL5 |
| Gene ID: |
85453 |
| Uniprot ID: |
TSYL5_HUMAN |
| Immunogen Region: |
201-383 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 201-383 of human TSPYL5 (NP_277047.2). |
| Immunogen Sequence: |
SMDTLENVQLKLENMNAQAD RAYLRLSRKFGQLRLQHLER RNHLIQNIPGFWGQAFQNHP QLASFLNSQEKEVLSYLNSL EVEELGLARLGYKIKFYFDR NPYFQNKVLIKEYGCGPSGQ VVSRSTPIQWLPGHDLQSLS QGNPENNRSFFGWFSNHSSI ESDKIVEIINEELWPNPLQF YLL |
| Function | Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination.the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7. |
| Protein Name | Testis-Specific Y-Encoded-Like Protein 5Tspy-Like Protein 5 |
| Alternative Antibody Names | Anti-Testis-Specific Y-Encoded-Like Protein 5 antibodyAnti-Tspy-Like Protein 5 antibodyAnti-TSPYL5 antibodyAnti-KIAA1750 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Immunohistochemistry analysis of SAV1 in paraffin-embedded Human colon using [KO Validated] SAV1 Rabbit polyclonal antibody (STJ11101465) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/90378/359716/STJ11101465_1__88301.1713124227.jpg?c=1 "Immunohistochemistry analysis of SAV1 in paraffin-embedded Human colon using [KO Validated] SAV1 Rabbit polyclonal antibody (STJ11101465) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.")
