| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TRIP13 (1-120) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TRIP13 |
| Gene ID: |
9319 |
| Uniprot ID: |
PCH2_HUMAN |
| Immunogen Region: |
1-120 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human TRIP13 (NP_004228.1). |
| Immunogen Sequence: |
MDEAVGDLKQALPCVAESPT VHVEVHQRGSSTAKKEDINL SVRKLLNRHNIVFGDYTWTE FDEPFLTRNVQSVSIIDTEL KVKDSQPIDLSACTVALHIF QLNEDGPSSENLEEETENII |
| Function | Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes. Plays a role in mitotic spindle assembly checkpoint (SAC) activation. |
| Protein Name | Pachytene Checkpoint Protein 2 HomologHuman Papillomavirus Type 16 E1 Protein-Binding Protein16e1-BpHpv16 E1 Protein-Binding ProteinThyroid Hormone Receptor Interactor 13Thyroid Receptor-Interacting Protein 13Tr-Interacting Protein 13Trip-13 |
| Alternative Antibody Names | Anti-Pachytene Checkpoint Protein 2 Homolog antibodyAnti-Human Papillomavirus Type 16 E1 Protein-Binding Protein antibodyAnti-16e1-Bp antibodyAnti-Hpv16 E1 Protein-Binding Protein antibodyAnti-Thyroid Hormone Receptor Interactor 13 antibodyAnti-Thyroid Receptor-Interacting Protein 13 antibodyAnti-Tr-Interacting Protein 13 antibodyAnti-Trip-13 antibodyAnti-TRIP13 antibodyAnti-PCH2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
