• Western blot analysis of 1, mouse-lung 2, mouse-brain 3, mouse-spleen cells using primary antibody diluted at 1:500 (4°C overnight). Secondary antibody：Goat Anti-rabbit IgG IRDye 800 ( diluted at 1:5000, 25°C, 1 hour)

Anti-TPM1 antibody (101-150 aa) (STJ99331)

SKU:
STJ99331

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Tropomyosin alpha-1 chain (101-150 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:10000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TPM1
Gene ID: 7168
Uniprot ID: TPM1_HUMAN
Immunogen Region: 101-150 aa
Specificity: Tropomyosin Alpha Polyclonal Antibody detects endogenous levels of Tropomyosin Alpha
Immunogen: Synthesized peptide derived from the human Tropomyosin Alpha at the amino acid range 101-150
Post Translational Modifications Phosphorylated at Ser-283 by DAPK1 in response to oxidative stress and this phosphorylation enhances stress fiber formation in endothelial cells.
Function Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Protein Name Tropomyosin Alpha-1 Chain
Alpha-Tropomyosin
Tropomyosin-1
Database Links Reactome: R-HSA-390522
Reactome: R-HSA-445355
Cellular Localisation Cytoplasm
Cytoskeleton
Associates With F-Actin Stress Fibers
Alternative Antibody Names Anti-Tropomyosin Alpha-1 Chain antibody
Anti-Alpha-Tropomyosin antibody
Anti-Tropomyosin-1 antibody
Anti-TPM1 antibody
Anti-C15orf13 antibody
Anti-TMSA antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance