| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-THSD4 (500-700) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
THSD4 |
| Gene ID: |
79875 |
| Uniprot ID: |
THSD4_HUMAN |
| Immunogen Region: |
500-700 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human THSD4 (NP_079093.2). |
| Immunogen Sequence: |
AEGPTNEILDVYMIHQQPNP GVHYEYVIMGTNAISPQVPP HRRPGEPFNGQMVTEGRSQE EGEQKGRNEEKEDLRGEAPE MFTSESAQTFPVRHPDRFSP HRPDNLVPPAPQPPRRSRDH NWKQLGTTECSTTCGKGSQY PIFRCVHRSTHEEAPESYCD SSMKPTPEEEPCNIFPCPAF WDIGEWSECSKTCGLGMQHR Q |
| Function | Promotes FBN1 matrix assembly. Attenuates TGFB signaling, possibly by accelerating the sequestration of large latent complexes of TGFB or active TGFB by FBN1 microfibril assembly, thereby negatively regulating the expression of TGFB regulatory targets, such as POSTN. |
| Protein Name | Thrombospondin Type-1 Domain-Containing Protein 4A Disintegrin And Metalloproteinase With Thrombospondin Motifs-Like Protein 6Adamts-Like Protein 6Adamtsl-6 |
| Database Links | Reactome: R-HSA-5083635Reactome: R-HSA-5173214 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Thrombospondin Type-1 Domain-Containing Protein 4 antibodyAnti-A Disintegrin And Metalloproteinase With Thrombospondin Motifs-Like Protein 6 antibodyAnti-Adamts-Like Protein 6 antibodyAnti-Adamtsl-6 antibodyAnti-THSD4 antibodyAnti-UNQ9334 antibodyAnti-PRO34005 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
