• Western blot analysis of lysates from SH-SY5Y cells, using THSD4 Rabbit polyclonal antibody (STJ119809) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-THSD4 antibody (500-700) (STJ119809)

SKU:
STJ119809

£112.50 - £522.50
Shipping:
Free Shipping
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-THSD4 (500-700) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: THSD4
Gene ID: 79875
Uniprot ID: THSD4_HUMAN
Immunogen Region: 500-700
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human THSD4 (NP_079093.2).
Immunogen Sequence: AEGPTNEILDVYMIHQQPNP GVHYEYVIMGTNAISPQVPP HRRPGEPFNGQMVTEGRSQE EGEQKGRNEEKEDLRGEAPE MFTSESAQTFPVRHPDRFSP HRPDNLVPPAPQPPRRSRDH NWKQLGTTECSTTCGKGSQY PIFRCVHRSTHEEAPESYCD SSMKPTPEEEPCNIFPCPAF WDIGEWSECSKTCGLGMQHR Q
Function Promotes FBN1 matrix assembly. Attenuates TGFB signaling, possibly by accelerating the sequestration of large latent complexes of TGFB or active TGFB by FBN1 microfibril assembly, thereby negatively regulating the expression of TGFB regulatory targets, such as POSTN.
Protein Name Thrombospondin Type-1 Domain-Containing Protein 4
A Disintegrin And Metalloproteinase With Thrombospondin Motifs-Like Protein 6
Adamts-Like Protein 6
Adamtsl-6
Database Links Reactome: R-HSA-5083635
Reactome: R-HSA-5173214
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Antibody Names Anti-Thrombospondin Type-1 Domain-Containing Protein 4 antibody
Anti-A Disintegrin And Metalloproteinase With Thrombospondin Motifs-Like Protein 6 antibody
Anti-Adamts-Like Protein 6 antibody
Anti-Adamtsl-6 antibody
Anti-THSD4 antibody
Anti-UNQ9334 antibody
Anti-PRO34005 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance