Anti-TGFA antibody (24-98) (STJ114390)

SKU:
STJ114390

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TGFA (24-98) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TGFA
Gene ID: 7039
Uniprot ID: TGFA_HUMAN
Immunogen Region: 24-98
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-98 of human TGFA (NP_001093161.1).
Immunogen Sequence: ENSTSPLSDPPVAAAVVSHF NDCPDSHTQFCFHGTCRFLV QEDKPACVCHSGYVGARCEH ADLLAVVAASQKKQA
Tissue Specificity Isoform 1, isoform 3 and isoform 4 are expressed in keratinocytes and tumor-derived cell lines.
Function TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
Protein Name Protransforming Growth Factor Alpha Cleaved Into - Transforming Growth Factor Alpha
Tgf-Alpha
Egf-Like Tgf
Etgf
Tgf Type 1
Database Links Reactome: R-HSA-1257604
Reactome: R-HSA-177929
Reactome: R-HSA-179812
Reactome: R-HSA-180292
Reactome: R-HSA-180336
Reactome: R-HSA-182971
Reactome: R-HSA-204005
Reactome: R-HSA-212718
Reactome: R-HSA-2219530
Reactome: R-HSA-5638303
Reactome: R-HSA-5673001
Reactome: R-HSA-5694530
Reactome: R-HSA-6811558
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Reactome: R-HSA-8866910
Reactome: R-HSA-9009391
Reactome: R-HSA-9018519
Reactome: R-HSA-9634638
Cellular Localisation Transforming Growth Factor Alpha: Secreted
Extracellular Space
Protransforming Growth Factor Alpha: Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Protransforming Growth Factor Alpha Cleaved Into - Transforming Growth Factor Alpha antibody
Anti-Tgf-Alpha antibody
Anti-Egf-Like Tgf antibody
Anti-Etgf antibody
Anti-Tgf Type 1 antibody
Anti-TGFA antibody

Information sourced from Uniprot.org

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