• Western blot analysis of extracts of various cell lines, using TERF1 antibody (STJ27246) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

Anti-TERF1 antibody (STJ27246)

SKU:
STJ27246
Current Stock:
Host: Rabbit
Applications: WB, IF
Reactivity: Human, Mouse
Short Description: Rabbit polyclonal primary antibody against TERF1.
Note: FOR RESEARCH USE ONLY (RUO).
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification: Affinity purification
Storage Instruction: Store at-20°C. Avoid freeze/thaw cycles.
Isotype: IgG
Dilution Range: WB: 1:500-1:2000
IF: 1:50-1:200
Uniprot ID: TERF1_HUMAN
Gene ID: 7013
Gene Symbol: TERF1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-419 of human TERF1 (NP_003209.2).
Background This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.
Tissue Specificity Highly expressed and ubiquitous. Isoform Pin2 predominates.
Database Links Reactome: R-HSA-110328
Cellular Localisation Nucleus
Cytoplasm
Cytoskeleton
Spindle
Chromosome
Telomere
Colocalizes With Telomeric Dna In Interphase And Prophase Cells
Telomeric Localization Decreases In Metaphase
Anaphase And Telophase
Associates With The Mitotic Spindle
Protein Name Telomeric Repeat-Binding Factor 1
Nima-Interacting Protein 2
Ttaggg Repeat-Binding Factor 1
Telomeric Protein Pin2/Trf1
Alternative Names Anti-Telomeric Repeat-Binding Factor 1 antibody
Anti-Nima-Interacting Protein 2 antibody
Anti-Ttaggg Repeat-Binding Factor 1 antibody
Anti-Telomeric Protein Pin2/Trf1 antibody
Anti-TERF1 antibody
Anti-PIN2 antibody
Anti-TRBF1 antibody
Anti-TRF antibody
Anti-TRF1 antibody
6 months standard