| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TCTN2 (420-670) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TCTN2 |
| Gene ID: |
79867 |
| Uniprot ID: |
TECT2_HUMAN |
| Immunogen Region: |
420-670 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 420-670 of human TCTN2 (NP_079085.2). |
| Immunogen Sequence: |
VKFLSYNSGNEEELSGNPGY QLGKPVRALNINRMNNVTTL HLWQSAGRGLCTSATFKPIL FGENVLSGCLLEVGINENCT QLRENAVERLDSLIQATHVA MRGNSDYADLSDGWLEIIRV DAPDPGADPLASSVNGMCLD IPAHLSIRILISDAGAVEGI TQQEILGVETRFSSVNWQYQ CGLTCEHKADLLPISASVQF IKIPAQLPHPLTRFQINYTE YDCNRNEVCWPQLLYPWTQ |
| Function | Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for hedgehog signaling transduction. |
| Protein Name | Tectonic-2 |
| Database Links | Reactome: R-HSA-5620912 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCytoplasmCytoskeletonCilium Basal BodyLocalizes At The Transition ZoneA Region Between The Basal Body And The Ciliary Axoneme |
| Alternative Antibody Names | Anti-Tectonic-2 antibodyAnti-TCTN2 antibodyAnti-C12orf38 antibodyAnti-TECT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
