Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-ITIH1 (530-670) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ITIH1 |
Gene ID: |
3697 |
Uniprot ID: |
ITIH1_HUMAN |
Immunogen Region: |
530-670 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 530-670 of human ITIH1 (NP_002206.2). |
Immunogen Sequence: |
HGEGQEFSITCLVDEEEMKK LLRERGHMLENHVERLWAYL TIQELLAKRMKVDREERANL SSQALQMSLDYGFVTPLTSM SIRGMADQDGLKPTIDKPSE DSPPLEMLGPRRTFVLSALQ PSPTHSSSNTQRLPDRVTGV D |
Post Translational Modifications | Heavy chains are linked to bikunin via chondroitin 4-sulfate esterified to the alpha-carboxyl of the C-terminal aspartate after propeptide cleavage. The S-linked glycan is composed of two 6-carbon sugars, possibly Glc or Gal. |
Function | May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. Contains a potential peptide which could stimulate a broad spectrum of phagocytotic cells. |
Protein Name | Inter-Alpha-Trypsin Inhibitor Heavy Chain H1Iti Heavy Chain H1Iti-Hc1Inter-Alpha-Inhibitor Heavy Chain 1Inter-Alpha-Trypsin Inhibitor Complex Component IiiSerum-Derived Hyaluronan-Associated ProteinShap |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Inter-Alpha-Trypsin Inhibitor Heavy Chain H1 antibodyAnti-Iti Heavy Chain H1 antibodyAnti-Iti-Hc1 antibodyAnti-Inter-Alpha-Inhibitor Heavy Chain 1 antibodyAnti-Inter-Alpha-Trypsin Inhibitor Complex Component Iii antibodyAnti-Serum-Derived Hyaluronan-Associated Protein antibodyAnti-Shap antibodyAnti-ITIH1 antibodyAnti-IGHEP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance