| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SUGT1 (159-333) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SUGT1 |
| Gene ID: |
10910 |
| Uniprot ID: |
SGT1_HUMAN |
| Immunogen Region: |
159-333 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 159-333 of human SUGT1 (NP_006695.1). |
| Immunogen Sequence: |
NVQKNDVNVEFSEKELSALV KLPSGEDYNLKLELLHPIIP EQSTFKVLSTKIEIKLKKPE AVRWEKLEGQGDVPTPKQFV ADVKNLYPSSSPYTRNWDKL VGEIKEEEKNEKLEGDAALN RLFQQIYSDGSDEVKRAMNK SFMESGGTVLSTNWSDVGKR KVEINPPDDMEWKKY |
| Post Translational Modifications | Phosphorylated at Ser-281 and Ser-331, dephosphorylation promotes nuclear translocation, most likely due to disruption of the SUGT1-HSP90 complex. |
| Function | May play a role in ubiquitination and subsequent proteasomal degradation of target proteins. |
| Protein Name | Protein Sgt1 HomologProtein 40-6-3Sgt1Suppressor Of G2 Allele Of Skp1 Homolog |
| Database Links | Reactome: R-HSA-844456Reactome: R-HSA-9660826 |
| Cellular Localisation | CytoplasmNucleusTranslocates To The Nucleus Upon Heat ShockRequiring S100a6 |
| Alternative Antibody Names | Anti-Protein Sgt1 Homolog antibodyAnti-Protein 40-6-3 antibodyAnti-Sgt1 antibodyAnti-Suppressor Of G2 Allele Of Skp1 Homolog antibodyAnti-SUGT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
