| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SUCLG2 (50-300) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SUCLG2 |
| Gene ID: |
8801 |
| Uniprot ID: |
SUCB2_HUMAN |
| Immunogen Region: |
50-300 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 50-300 of human SUCLG2 (NP_003839.2). |
| Immunogen Sequence: |
SDNGVRVQRFFVADTANEAL EAAKRLNAKEIVLKAQILAG GRGKGVFNSGLKGGVHLTKD PNVVGQLAKQMIGYNLATKQ TPKEGVKVNKVMVAEALDIS RETYLAILMDRSCNGPVLVG SPQGGVDIEEVAASNPELIF KEQIDIFEGIKDSQAQRMAE NLGFVGPLKSQAADQITKLY NLFLKIDATQVEVNPFGETP EGQVVCFDAKINFDDNAEFR QKDIFAMDDKSENEPIENE |
| Tissue Specificity | Mainly expressed in liver, kidney, heart, spleen and skeletal muscle. Also found in intestine and colon, and in low amounts in lung, brain, prostate, testis and ovary. |
| Function | GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. |
| Protein Name | Succinate--Coa Ligase Gdp-Forming Subunit Beta - MitochondrialGtp-Specific Succinyl-Coa Synthetase Subunit BetaG-ScsGtpscsSuccinyl-Coa Synthetase Beta-G ChainScs-Betag |
| Database Links | Reactome: R-HSA-71403 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Succinate--Coa Ligase Gdp-Forming Subunit Beta - Mitochondrial antibodyAnti-Gtp-Specific Succinyl-Coa Synthetase Subunit Beta antibodyAnti-G-Scs antibodyAnti-Gtpscs antibodyAnti-Succinyl-Coa Synthetase Beta-G Chain antibodyAnti-Scs-Betag antibodyAnti-SUCLG2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
