| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-STX5 (55-355) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
STX5 |
| Gene ID: |
6811 |
| Uniprot ID: |
STX5_HUMAN |
| Immunogen Region: |
55-355 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 55-355 of human STX5 (NP_003155.2). |
| Immunogen Sequence: |
MSCRDRTQEFLSACKSLQTR QNGIQTNKPALRAVRQRSEF TLMAKRIGKDLSNTFAKLEK LTILAKRKSLFDDKAVEIEE LTYIIKQDINSLNKQIAQLQ DFVRAKGSQSGRHLQTHSNT IVVSLQSKLASMSNDFKSVL EVRTENLKQQRSRREQFSRA PVSALPLAPNHLGGGAVVLG AESHASKDVAIDMMDSRTSQ QLQLIDEQDSYIQSRADTMQ NIESTIVELGSIFQQLAHM |
| Function | Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. (Microbial infection) Required for the efficient production of infectious virion during human cytomegalovirus infection. Mechanistically, participates in the formation of the cytoplasmic viral assembly compartment where tegument acquisition and envelopment occur. |
| Protein Name | Syntaxin-5 |
| Database Links | Reactome: R-HSA-204005Reactome: R-HSA-5694530Reactome: R-HSA-6807878Reactome: R-HSA-6811438Reactome: R-HSA-8980692Reactome: R-HSA-9013106Reactome: R-HSA-9013408Reactome: R-HSA-9609523 |
| Cellular Localisation | Endoplasmic Reticulum-Golgi Intermediate Compartment MembraneSingle-Pass Type Iv Membrane ProteinGolgi Apparatus MembraneLocalizes Throughout The Golgi ApparatusBut Most Abundant In The Cis-Most Cisternae |
| Alternative Antibody Names | Anti-Syntaxin-5 antibodyAnti-STX5 antibodyAnti-STX5A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
