Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-STBD1 (24-200) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
STBD1 |
Gene ID: |
8987 |
Uniprot ID: |
STBD1_HUMAN |
Immunogen Region: |
24-200 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 24-200 of human STBD1 (NP_003934.1). |
Immunogen Sequence: |
RGGPGDTGKDGDAEQEKDAP LGGAAIPGGHQSGSSGLSPG PSGQELVTKPEHLQESNGHL ISKTKDLGKLQAASWRLQNP SREVCDNSREHVPSGQFPDT EAPATSETSNSRSYSEVSRN ESLESPMGEWGFQKGQEISA KAATCFAEKLPSSNLLKNRA KEEMSLSDLNSQDRVDH |
Tissue Specificity | Expressed at high level in skeletal and cardiac muscles. Moderately expressed in liver and placenta. No expression is found in pancreas, kidney or lung. Present in skeletal muscle, heart and placenta (at protein level). |
Post Translational Modifications | Ubiquitinated, which leads to proteasomal degradation. |
Function | Acts as a cargo receptor for glycogen. Delivers its cargo to an autophagic pathway called glycophagy, resulting in the transport of glycogen to lysosomes. |
Protein Name | Starch-Binding Domain-Containing Protein 1Genethonin-1Glycophagy Cargo Receptor Stbd1 |
Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-8980692Reactome: R-HSA-9013404Reactome: R-HSA-9013405Reactome: R-HSA-9013408Reactome: R-HSA-9013423 |
Cellular Localisation | Preautophagosomal Structure MembraneSingle-Pass Type Iii Membrane ProteinEndoplasmic Reticulum MembraneCell MembraneSarcolemmaT-TubuleAlso Detected Near The Junctional Sarcoplasmic ReticulumConcentrates At Perinuclear Structures |
Alternative Antibody Names | Anti-Starch-Binding Domain-Containing Protein 1 antibodyAnti-Genethonin-1 antibodyAnti-Glycophagy Cargo Receptor Stbd1 antibodyAnti-STBD1 antibodyAnti-GENX-3414 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance