• Western blot analysis of extracts of various cell lines, using SSR1 Antibody (STJ111212) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 20s.

Anti-SSR1 antibody (19-207) (STJ111212)

SKU:
STJ111212

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SSR1 (19-207) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SSR1
Gene ID: 6745
Uniprot ID: SSRA_HUMAN
Immunogen Region: 19-207
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 19-207 of human SSR1 (NP_003135.2).
Immunogen Sequence: VLFRGGPRGLLAVAQDLTED EETVEDSIIEDEDDEAEVEE DEPTDLVEDKEEEDVSGEPE ASPSADTTILFVKGEDFPAN NIVKFLVGFTNKGTEDFIVE SLDASFRYPQDYQFYIQNFT ALPLNTVVPPQRQATFEYSF IPAEPMGGRPFGLVINLNYK DLNGNVFQDAVFNQTVTVIE REDGLDGET
Function TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.
Protein Name Translocon-Associated Protein Subunit Alpha
Trap-Alpha
Signal Sequence Receptor Subunit Alpha
Ssr-Alpha
Database Links Reactome: R-HSA-1799339
Reactome: R-HSA-381038
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Translocon-Associated Protein Subunit Alpha antibody
Anti-Trap-Alpha antibody
Anti-Signal Sequence Receptor Subunit Alpha antibody
Anti-Ssr-Alpha antibody
Anti-SSR1 antibody
Anti-TRAPA antibody
Anti-PSEC0262 antibody

Information sourced from Uniprot.org

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