| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SPG11 (550-750) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SPG11 |
| Gene ID: |
80208 |
| Uniprot ID: |
SPTCS_HUMAN |
| Immunogen Region: |
550-750 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 550-750 of human SPG11 (NP_079413.3). |
| Immunogen Sequence: |
KSKENLFNPSSKSSVSDQFD HLSSHLYLRNVEELIPALDL LCSAIRESYSEPQSKHFSEQ LLNLTLSFLNNQIKELFIHT EELDEHLQKGVNILTSYINE LRTFMIKFPWKLTDAIDEYD VHENVPKVKESNIWKKLSFE EVIASAILNNKIPEAQTFFR IDSHSAQKLEELIGIGLNLV FDNLKKNNIKEASELLKNMG F |
| Tissue Specificity | Expressed in all structures of brain, with a high expression in cerebellum. Expressed in cortical projection neurons. |
| Function | May play a role in neurite plasticity by maintaining cytoskeleton stability and regulating synaptic vesicle transport. |
| Protein Name | SpatacsinColorectal Carcinoma-Associated ProteinSpastic Paraplegia 11 Protein |
| Cellular Localisation | CytoplasmCytosolNucleusCell ProjectionAxonDendriteMainly Cytoplasmic |
| Alternative Antibody Names | Anti-Spatacsin antibodyAnti-Colorectal Carcinoma-Associated Protein antibodyAnti-Spastic Paraplegia 11 Protein antibodyAnti-SPG11 antibodyAnti-KIAA1840 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using [KO Validated] NCOA2 Rabbit polyclonal antibody (STJ112318) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/92369/372743/STJ112318_1__72291.1713138814.jpg?c=1 "Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using [KO Validated] NCOA2 Rabbit polyclonal antibody (STJ112318) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.")
