• Western blot analysis of lysates from wild type (WT) and SND1 knockout (KO) HeLa cells, using [KO Validated] SND1 Rabbit polyclonal antibody (STJ115376) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
  • Western blot analysis of various lysates using [KO Validated] SND1 Rabbit polyclonal antibody (STJ115376) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-SND1 antibody (26-285) (STJ115376)

SKU:
STJ115376

£129.50 - £639.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SND1 (26-285) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SND1
Gene ID: 27044
Uniprot ID: SND1_HUMAN
Immunogen Region: 26-285
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-285 of human SND1 (NP_055205.2).
Immunogen Sequence: MVLSGCAIIVRGQPRGGPPP ERQINLSNIRAGNLARRAAA TQPDAKDTPDEPWAFPAREF LRKKLIGKEVCFTIENKTPQ GREYGMIYLGKDTNGENIAE SLVAEGLATRREGMRANNPE QNRLSECEEQAKAAKKGMWS EGNGSHTIRDLKYTIENPRH FVDSHHQKPVNAIIEHVRDG SVVRALLLPDYYLVTVMLSG IKCPTFRREADGSETPEPFA AEAKFFTESRLLQRDVQII
Tissue Specificity Ubiquitously expressed.
Post Translational Modifications Phosphorylated by PIM1 in vitro.
Function Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition. Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for STAT5. (Microbial infection) Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).
Protein Name Staphylococcal Nuclease Domain-Containing Protein 1
100 Kda Coactivator
Ebna2 Coactivator P100
Tudor Domain-Containing Protein 11
P100 Co-Activator
Database Links Reactome: R-HSA-6802952
Cellular Localisation Cytoplasm
Nucleus
Melanosome
In Il-4 Stimulated Cells Colocalizes With Stat6 In The Nucleus
Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Alternative Antibody Names Anti-Staphylococcal Nuclease Domain-Containing Protein 1 antibody
Anti-100 Kda Coactivator antibody
Anti-Ebna2 Coactivator P100 antibody
Anti-Tudor Domain-Containing Protein 11 antibody
Anti-P100 Co-Activator antibody
Anti-SND1 antibody
Anti-TDRD11 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance