| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC30A6 (252-461) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC30A6 |
| Gene ID: |
55676 |
| Uniprot ID: |
ZNT6_HUMAN |
| Immunogen Region: |
252-461 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 252-461 of human SLC30A6 (NP_060434.2). |
| Immunogen Sequence: |
KVLLQTTPPHVIGQLDKLIR EVSTLDGVLEVRNEHFWTLG FGSLAGSVHVRIRRDANEQM VLAHVTNRLYTLVSTLTVQI FKDDWIRPALLSGPVAANVL NFSDHHVIPMPLLKGTDDLN PVTSTPAKPSSPPPEFSFNT PGKNVNPVILLNTQTRPYGF GLNHGHTPYSSMLNQGLGVP GIGATQGLRTGFTNIPSRYG TNNRIGQPRP |
| Tissue Specificity | Expressed in brain.especially in cerebellum, hippocampus, parahippocampal gyrus, superior and middle temporal gyrus. Also expressed in B-cells, colon, eye, and lung. Lower expression was present in bone, brain, cervix, ear, heart, kidney, muscle, nerve, pancreas, prostate, skin, stomach, and testis. |
| Function | Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory pathway. As part of that zinc ion:proton antiporter, contributes to zinc ion homeostasis within the early secretory pathway and regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis. |
| Protein Name | Zinc Transporter 6Znt-6Solute Carrier Family 30 Member 6 |
| Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Zinc Transporter 6 antibodyAnti-Znt-6 antibodyAnti-Solute Carrier Family 30 Member 6 antibodyAnti-SLC30A6 antibodyAnti-ZNT6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
