| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC13A3 (160-240) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC13A3 |
| Gene ID: |
64849 |
| Uniprot ID: |
S13A3_HUMAN |
| Immunogen Region: |
160-240 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 160-240 of human SLC13A3 (NP_073740.2). |
| Immunogen Sequence: |
KSLFGQKEVRKDPSQESEEN TAAVRRNGLHTVPTEMQFLA STEAKDHPGETEVPLDLPAD SRKEDEYRRNIWKGFLISIP Y |
| Tissue Specificity | Expression is highest in kidney. Detected in placenta, brain, liver and pancreas. |
| Function | High-affinity sodium-dicarboxylate cotransporter that accepts a range of substrates with 4-6 carbon atoms, such as the citric acid cycle intermediates succinate and alpha-ketoglutarate (2-oxoglutarate), as well as other compounds including N-acetyl-L-aspartate. Transports the dicarboxylate into the cell with a probable stoichiometry of 3 Na(+) for 1 divalent dicarboxylate, rendering the process electrogenic. Can transport citrate in a Na(+)-dependent manner, recognizing the divalent form of citrate rather than the trivalent form which is normally found in blood. |
| Protein Name | Na(+/Dicarboxylate Cotransporter 3Nadc-3Hnadc3Na(+-Coupled Carboxylate Transporter 3Nac3Sodium-Dependent High-Affinity Dicarboxylate Transporter 2Solute Carrier Family 13 Member 3Slc13a3 |
| Database Links | Reactome: R-HSA-433137 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Na(+/Dicarboxylate Cotransporter 3 antibodyAnti-Nadc-3 antibodyAnti-Hnadc3 antibodyAnti-Na(+-Coupled Carboxylate Transporter 3 antibodyAnti-Nac3 antibodyAnti-Sodium-Dependent High-Affinity Dicarboxylate Transporter 2 antibodyAnti-Solute Carrier Family 13 Member 3 antibodyAnti-Slc13a3 antibodyAnti-SLC13A3 antibodyAnti-NADC3 antibodyAnti-SDCT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
