| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SF3B5 (1-86) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SF3B5 |
| Gene ID: |
83443 |
| Uniprot ID: |
SF3B5_HUMAN |
| Immunogen Region: |
1-86 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-86 of human SF3B5 (NP_112577.1). |
| Immunogen Sequence: |
MTDRYTIHSQLEHLQSKYIG TGHADTTKWEWLVNQHRDSY CSYMGHFDLLNYFAIAENES KARVRFNLMEKMLQPCGPPA DKPEEN |
| Function | Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). |
| Protein Name | Splicing Factor 3b Subunit 5Sf3b5Pre-Mrna-Splicing Factor Sf3b 10 Kda Subunit |
| Database Links | Reactome: R-HSA-72163Reactome: R-HSA-72165 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Splicing Factor 3b Subunit 5 antibodyAnti-Sf3b5 antibodyAnti-Pre-Mrna-Splicing Factor Sf3b 10 Kda Subunit antibodyAnti-SF3B5 antibodyAnti-SF3B10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
