Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-SF3A2 (1-220) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SF3A2 |
Gene ID: |
8175 |
Uniprot ID: |
SF3A2_HUMAN |
Immunogen Region: |
1-220 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SF3A2 (NP_009096.2). |
Immunogen Sequence: |
MDFQHRPGGKTGSGGVASSS ESNRDRRERLRQLALETIDI NKDPYFMKNHLGSYECKLCL TLHNNEGSYLAHTQGKKHQT NLARRAAKEAKEAPAQPAPE KVKVEVKKFVKIGRPGYKVT KQRDSEMGQQSLLFQIDYPE IAEGIMPRHRFMSAYEQRIE PPDRRWQYLLMAAEPYETIA FKVPSREIDKAEGKFWTHWN RETKQFFLQFHFKMEKPPAP |
Function | Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes, including the Bact complex. Interacts directly with the duplex formed by U2 snRNA and the intron. |
Protein Name | Splicing Factor 3a Subunit 2Sf3a66Spliceosome-Associated Protein 62Sap 62 |
Database Links | Reactome: R-HSA-72163 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Splicing Factor 3a Subunit 2 antibodyAnti-Sf3a66 antibodyAnti-Spliceosome-Associated Protein 62 antibodyAnti-Sap 62 antibodyAnti-SF3A2 antibodyAnti-SAP62 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance