Host: |
Rabbit |
Applications: |
WB/IHC |
Reactivity: |
Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-SERPINF2 (302-491) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:100 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SERPINF2 |
Gene ID: |
5345 |
Uniprot ID: |
A2AP_HUMAN |
Immunogen Region: |
302-491 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 302-491 of human SERPINF2 (NP_001159392.1). |
Immunogen Sequence: |
VPTHFEWNVSQVLANLSWDT LHPPLVWERPTKVRLPKLYL KHQMDLVATLSQLGLQELFQ APDLRGISEQSLVVSGVQHQ STLELSEVGVEAAAATSIAM SRMSLSSFSVNRPFLFFIFE DTTGLPLFVGSVRNPNPSAP RELKEQQDSPGNKDFLQSLK GFPRGDKLFGPDLKLVPPME EDYPQFGSPK |
Tissue Specificity | Expressed by the liver and secreted in plasma. |
Post Translational Modifications | Proteolytically cleaved at Pro-39 by both the prolyl endopeptidase FAP form and antiplasmin-cleaving enzyme FAP soluble form to generate mature alpha-2-antiplasmin. |
Function | Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin. |
Protein Name | Alpha-2-AntiplasminAlpha-2-ApAlpha-2-Plasmin InhibitorAlpha-2-PiSerpin F2 |
Database Links | Reactome: R-HSA-114608Reactome: R-HSA-75205 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Alpha-2-Antiplasmin antibodyAnti-Alpha-2-Ap antibodyAnti-Alpha-2-Plasmin Inhibitor antibodyAnti-Alpha-2-Pi antibodyAnti-Serpin F2 antibodyAnti-SERPINF2 antibodyAnti-AAP antibodyAnti-PLI antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance