Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-SERPINA12 (20-320) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SERPINA12 |
Gene ID: |
145264 |
Uniprot ID: |
SPA12_HUMAN |
Immunogen Region: |
20-320 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human SERPINA12 (NP_776249.1). |
Immunogen Sequence: |
LLKPSFSPRNYKALSEVQGW KQRMAAKELARQNMDLGFKL LKKLAFYNPGRNIFLSPLSI STAFSMLCLGAQDSTLDEIK QGFNFRKMPEKDLHEGFHYI IHELTQKTQDLKLSIGNTLF IDQRLQPQRKFLEDAKNFYS AETILTNFQNLEMAQKQIND FISQKTHGKINNLIENIDPG TVMLLANYIFFRARWKHEFD PNVTKEEDFFLEKNSSVKVP MMFRSGIYQVGYDDKLSCT |
Tissue Specificity | Expressed in visceral adipose tissues. |
Post Translational Modifications | Glycosylation slightly decreases affinity for heparin, but otherwise has no significant effect on KLK7 inhibitory activity or thermal stability of the protein. |
Function | Adipokine that modulates insulin action by specifically inhibiting its target protease KLK7 in white adipose tissues. |
Protein Name | Serpin A12Ol-64Visceral Adipose Tissue-Derived Serine Protease InhibitorVaspinVisceral Adipose-Specific Serpin |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Serpin A12 antibodyAnti-Ol-64 antibodyAnti-Visceral Adipose Tissue-Derived Serine Protease Inhibitor antibodyAnti-Vaspin antibodyAnti-Visceral Adipose-Specific Serpin antibodyAnti-SERPINA12 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance