| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SENP8 (1-212) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SENP8 |
| Gene ID: |
123228 |
| Uniprot ID: |
SENP8_HUMAN |
| Immunogen Region: |
1-212 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human SENP8 (NP_660205.3). |
| Immunogen Sequence: |
MDPVVLSYMDSLLRQSDVSL LDPPSWLNDHIIGFAFEYFA NSQFHDCSDHVSFISPEVTQ FIKCTSNPAEIAMFLEPLDL PNKRVVFLAINDNSNQAAGG THWSLLVYLQDKNSFFHYDS HSRSNSVHAKQVAEKLEAFL GRKGDKLAFVEEKAPAQQNS YDCGMYVICNTEALCQNFFR QQTESLLQLLTPAYITKKRG EWKDLITTLAKK |
| Tissue Specificity | Broadly expressed, with highest levels in kidney and pancreas. |
| Function | Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53. |
| Protein Name | Sentrin-Specific Protease 8Deneddylase-1Nedd8-Specific Protease 1Protease - Cysteine 2Sentrin/Sumo-Specific Protease Senp8 |
| Database Links | Reactome: R-HSA-5689603Reactome: R-HSA-8951664 |
| Alternative Antibody Names | Anti-Sentrin-Specific Protease 8 antibodyAnti-Deneddylase-1 antibodyAnti-Nedd8-Specific Protease 1 antibodyAnti-Protease - Cysteine 2 antibodyAnti-Sentrin/Sumo-Specific Protease Senp8 antibodyAnti-SENP8 antibodyAnti-DEN1 antibodyAnti-NEDP1 antibodyAnti-PRSC2 antibodyAnti-FKSG8 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and PAK2 knockout (KO) HeLa cells, using [KO Validated] PAK2 Rabbit polyclonal antibody (STJ11100066) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89136/357585/STJ11100066_1__93634.1713121719.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and PAK2 knockout (KO) HeLa cells, using [KO Validated] PAK2 Rabbit polyclonal antibody (STJ11100066) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.")
