| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SEC31A (300-500) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SEC31A |
| Gene ID: |
22872 |
| Uniprot ID: |
SC31A_HUMAN |
| Immunogen Region: |
300-500 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 300-500 of human SEC31A (NP_055748.2). |
| Immunogen Sequence: |
PTNTQWCFDIQWCPRNPAVL SAASFDGRISVYSIMGGSTD GLRQKQVDKLSSSFGNLDPF GTGQPLPPLQIPQQTAQHSI VLPLKKPPKWIRRPVGASFS FGGKLVTFENVRMPSHQGAE QQQQQHHVFISQVVTEKEFL SRSDQLQQAVQSQGFINYCQ KKIDASQTEFEKNVWSFLKV NFEDDSRGKYLELLGYRKED L |
| Tissue Specificity | Abundantly and ubiquitously expressed. |
| Post Translational Modifications | Monoubiquitinated by the BCR(KLHL12) E3 ubiquitin ligase complex, leading to regulate the size of COPII coats. |
| Function | Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. |
| Protein Name | Protein Transport Protein Sec31aAbp125Abp130Sec31-Like Protein 1Sec31-Related Protein AWeb1-Like Protein |
| Database Links | Reactome: R-HSA-204005Reactome: R-HSA-2132295Reactome: R-HSA-381038Reactome: R-HSA-9725370Reactome: R-HSA-983170 |
| Cellular Localisation | CytoplasmCytoplasmic VesicleCopii-Coated Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideEndoplasmic Reticulum MembraneCytosolAssociates With Membranes In A Gtp-Dependent MannerLocalizes To Endoplasmic Reticulum Exit Sites (Eres)Also Known As Transitional Endoplasmic Reticulum (Ter) |
| Alternative Antibody Names | Anti-Protein Transport Protein Sec31a antibodyAnti-Abp125 antibodyAnti-Abp130 antibodyAnti-Sec31-Like Protein 1 antibodyAnti-Sec31-Related Protein A antibodyAnti-Web1-Like Protein antibodyAnti-SEC31A antibodyAnti-KIAA0905 antibodyAnti-SEC31L1 antibodyAnti-HSPC275 antibodyAnti-HSPC334 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
