| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SCNN1D |
| Gene ID: | 6339 |
| Uniprot ID: | SCNND_HUMAN |
| Immunogen Region: | 540-680 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 540-680 of human SCNN1D (NP_001123885.2). |
| Immunogen Sequence: | GVEVELLHNTSYTRQACLVS CFQQLMVETCSCGYYLHPLP AGAEYCSSARHPAWGHCFYR LYQDLETHRLPCTSRCPRPC RESAFKLSTGTSRWPSAKSA GWTLATLGEQGLPHQSHRQR SSLAKINIVYQELNYRSVEE A |
| Function | Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. |
| Protein Name | Amiloride-Sensitive Sodium Channel Subunit DeltaDelta-NachEpithelial Na(+ Channel Subunit DeltaDelta-EnacEnacdNonvoltage-Gated Sodium Channel 1 Subunit DeltaScned |
| Database Links | Reactome: R-HSA-2672351Reactome: R-HSA-9730628 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Amiloride-Sensitive Sodium Channel Subunit Delta antibodyAnti-Delta-Nach antibodyAnti-Epithelial Na(+ Channel Subunit Delta antibodyAnti-Delta-Enac antibodyAnti-Enacd antibodyAnti-Nonvoltage-Gated Sodium Channel 1 Subunit Delta antibodyAnti-Scned antibodyAnti-SCNN1D antibodyAnti-DNACH antibody |
Information sourced from Uniprot.org