• Western blot analysis of extracts of various cell lines, using SCNN1D antibody (STJ112280) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-SCNN1D antibody (540-680) (STJ112280)

SKU:
STJ112280

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SCNN1D (540-680) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SCNN1D
Gene ID: 6339
Uniprot ID: SCNND_HUMAN
Immunogen Region: 540-680
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 540-680 of human SCNN1D (NP_001123885.2).
Immunogen Sequence: GVEVELLHNTSYTRQACLVS CFQQLMVETCSCGYYLHPLP AGAEYCSSARHPAWGHCFYR LYQDLETHRLPCTSRCPRPC RESAFKLSTGTSRWPSAKSA GWTLATLGEQGLPHQSHRQR SSLAKINIVYQELNYRSVEE A
Function Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Protein Name Amiloride-Sensitive Sodium Channel Subunit Delta
Delta-Nach
Epithelial Na(+ Channel Subunit Delta
Delta-Enac
Enacd
Nonvoltage-Gated Sodium Channel 1 Subunit Delta
Scned
Database Links Reactome: R-HSA-2672351
Reactome: R-HSA-9730628
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Amiloride-Sensitive Sodium Channel Subunit Delta antibody
Anti-Delta-Nach antibody
Anti-Epithelial Na(+ Channel Subunit Delta antibody
Anti-Delta-Enac antibody
Anti-Enacd antibody
Anti-Nonvoltage-Gated Sodium Channel 1 Subunit Delta antibody
Anti-Scned antibody
Anti-SCNN1D antibody
Anti-DNACH antibody

Information sourced from Uniprot.org

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