• Western blot analysis of extracts of various cell lines, using RXFP3 antibody (STJ112341) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 20s.

Anti-RXFP3 antibody (1-80) (STJ112341)

SKU:
STJ112341

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-RXFP3 (1-80) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RXFP3
Gene ID: 51289
Uniprot ID: RL3R1_HUMAN
Immunogen Region: 1-80
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human RXFP3 (NP_057652.1).
Immunogen Sequence: MQMADAATIATMNKAAGGDK LAELFSLVPDLLEAANTSGN ASLQLPDLWWELGLELPDGA PPGHPPGSGGAESADTEARV
Tissue Specificity Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.
Function Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.
Protein Name Relaxin-3 Receptor 1
Rln3 Receptor 1
G Protein-Coupled Receptor Salpr
G-Protein Coupled Receptor Gpcr135
Relaxin Family Peptide Receptor 3
Somatostatin- And Angiotensin-Like Peptide Receptor
Database Links Reactome: R-HSA-418594
Reactome: R-HSA-444821
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Relaxin-3 Receptor 1 antibody
Anti-Rln3 Receptor 1 antibody
Anti-G Protein-Coupled Receptor Salpr antibody
Anti-G-Protein Coupled Receptor Gpcr135 antibody
Anti-Relaxin Family Peptide Receptor 3 antibody
Anti-Somatostatin- And Angiotensin-Like Peptide Receptor antibody
Anti-RXFP3 antibody
Anti-GPCR135 antibody
Anti-RLN3R1 antibody
Anti-SALPR antibody

Information sourced from Uniprot.org

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