| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RNF17 |
| Gene ID: | 56163 |
| Uniprot ID: | RNF17_HUMAN |
| Immunogen Region: | 900-1200 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 900-1200 of human RNF17 (NP_112567.2). |
| Immunogen Sequence: | VSAKSLPNENFQSLYNKELP VHICNVISPEKIYVQWLLTE NLLNSLEEKMIAAYENSKWE PVKWENDMHCAVKIQDKNQW RRGQIIRMVTDTLVEVLLYD VGVELVVNVDCLRKLEENLK TMGRLSLECSLVDIRPAGGS DKWTATACDCLSLYLTGAVA TIILQVDSEENNTTWPLPVK IFCRDEKGERVDVSKYLIKK GLALRERRINNLDNSHSLSE KSLEVPLEQEDSVVTNCIK |
| Tissue Specificity | Testis specific. |
| Function | Seems to be involved in regulation of transcriptional activity of MYC. In vitro, inhibits DNA-binding activity of Mad-MAX heterodimers. Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. May be involved in spermiogenesis. |
| Protein Name | Ring Finger Protein 17Tudor Domain-Containing Protein 4 |
| Cellular Localisation | CytoplasmNucleusPredominantly Found In The CytoplasmComponent Of A Nuage In Male Germ Cells (An Electron-Dense Spherical Cytoplasmic Body Present In Late Pachytene And Diplotene Spermatocytes And In Elonging Spermatids) |
| Alternative Antibody Names | Anti-Ring Finger Protein 17 antibodyAnti-Tudor Domain-Containing Protein 4 antibodyAnti-RNF17 antibodyAnti-TDRD4 antibody |
Information sourced from Uniprot.org