| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RNF17 (900-1200) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RNF17 |
| Gene ID: |
56163 |
| Uniprot ID: |
RNF17_HUMAN |
| Immunogen Region: |
900-1200 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 900-1200 of human RNF17 (NP_112567.2). |
| Immunogen Sequence: |
VSAKSLPNENFQSLYNKELP VHICNVISPEKIYVQWLLTE NLLNSLEEKMIAAYENSKWE PVKWENDMHCAVKIQDKNQW RRGQIIRMVTDTLVEVLLYD VGVELVVNVDCLRKLEENLK TMGRLSLECSLVDIRPAGGS DKWTATACDCLSLYLTGAVA TIILQVDSEENNTTWPLPVK IFCRDEKGERVDVSKYLIKK GLALRERRINNLDNSHSLSE KSLEVPLEQEDSVVTNCIK |
| Tissue Specificity | Testis specific. |
| Function | Seems to be involved in regulation of transcriptional activity of MYC. In vitro, inhibits DNA-binding activity of Mad-MAX heterodimers. Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. May be involved in spermiogenesis. |
| Protein Name | Ring Finger Protein 17Tudor Domain-Containing Protein 4 |
| Cellular Localisation | CytoplasmNucleusPredominantly Found In The CytoplasmComponent Of A Nuage In Male Germ Cells (An Electron-Dense Spherical Cytoplasmic Body Present In Late Pachytene And Diplotene Spermatocytes And In Elonging Spermatids) |
| Alternative Antibody Names | Anti-Ring Finger Protein 17 antibodyAnti-Tudor Domain-Containing Protein 4 antibodyAnti-RNF17 antibodyAnti-TDRD4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
