| Host: |
Rabbit |
| Applications: |
WB/IHC/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RHOD (153-171) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RHOD |
| Gene ID: |
29984 |
| Uniprot ID: |
RHOD_HUMAN |
| Immunogen Region: |
153-171 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 153-171 of human RHOD (NP_055393.1). |
| Immunogen Sequence: |
YHRGQEMARSVGAVAYLEC |
| Tissue Specificity | Heart, placenta, liver, skeletal muscle, and pancreas and, with weaker intensity, in several other tissues. |
| Function | Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Participates in the reorganization of actin cytoskeleton.the function seems to involve WHAMM and includes regulation of filopodia formation and actin filament bundling. Can modulate the effect of DAPK3 in reorganization of actin cytoskeleton and focal adhesion dissolution. |
| Protein Name | Rho-Related Gtp-Binding Protein RhodRho-Related Protein Hp1Rhohp1 |
| Database Links | Reactome: R-HSA-5663220Reactome: R-HSA-9013405 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic SideEarly EndosomeColocalizes With Rab5 To Early Endosomes |
| Alternative Antibody Names | Anti-Rho-Related Gtp-Binding Protein Rhod antibodyAnti-Rho-Related Protein Hp1 antibodyAnti-Rhohp1 antibodyAnti-RHOD antibodyAnti-ARHD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
