• Western blot analysis of various lysates using STAC Rabbit polyclonal antibody (STJ117514) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-STAC antibody (153-402) (STJ117514)

SKU:
STJ117514

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-STAC (153-402) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: STAC
Gene ID: 6769
Uniprot ID: STAC_HUMAN
Immunogen Region: 153-402
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 153-402 of human STAC (NP_003140.1).
Immunogen Sequence: GLAPQRCMGKLPKGFRRYYS SPLLIHEQFGCIKEVMPIAC GNKVDPVYETLRFGTSLAQR TKKGSSGSGSDSPHRTSTSD LVEVPEEANGPGGGYDLRKR SNSVFTYPENGTDDFRDPAK NINHQGSLSKDPLQMNTYVA LYKFVPQENEDLEMRPGDII TLLEDSNEDWWKGKIQDRIG FFPANFVQRLQQNEKIFRCV RTFIGCKEQGQITLKENQIC VSSEEEQDGFIRVLSGKKK
Function Promotes expression of the ion channel CACNA1H at the cell membrane, and thereby contributes to the regulation of channel activity. Plays a minor and redundant role in promoting the expression of calcium channel CACNA1S at the cell membrane, and thereby contributes to increased channel activity. Slows down the inactivation rate of the calcium channel CACNA1C.
Protein Name Sh3 And Cysteine-Rich Domain-Containing Protein
Src Homology 3 And Cysteine-Rich Domain-Containing Protein
Cellular Localisation Cytoplasm
Cytosol
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Sarcolemma
Alternative Antibody Names Anti-Sh3 And Cysteine-Rich Domain-Containing Protein antibody
Anti-Src Homology 3 And Cysteine-Rich Domain-Containing Protein antibody
Anti-STAC antibody
Anti-STAC1 antibody

Information sourced from Uniprot.org

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