| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RELT |
| Gene ID: | 84957 |
| Uniprot ID: | TR19L_HUMAN |
| Immunogen Region: | 26-162 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-162 of human RELT (NP_116260.2). |
| Immunogen Sequence: | STTLWQCPPGEEPDLDPGQG TLCRPCPPGTFSAAWGSSPC QPHARCSLWRRLEAQVGMAT RDTLCGDCWPGWFGPWGVPR VPCQPCSWAPLGTHGCDEWG RRARRGVEVAAGASSGGETR QPGNGTRAGGPEETAAQ |
| Tissue Specificity | Spleen, lymph node, brain, breast and peripheral blood leukocytes (at protein level). Expressed highly in bone marrow and fetal liver. Very low levels in skeletal muscle, testis and colon. Not detected in kidney and pancreas. |
| Post Translational Modifications | Phosphorylated in vitro by OXSR1. Phosphorylated by STK39. |
| Function | May play a role in apoptosis. Induces activation of MAPK14/p38 and MAPK8/JNK MAPK cascades, when overexpressed. Involved in dental enamel formation. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 19l Receptor Expressed In Lymphoid Tissues |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein Cytoplasm Perinuclear Region |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 19l antibody Anti-Receptor Expressed In Lymphoid Tissues antibody Anti-RELT antibody Anti-TNFRSF19L antibody |
Information sourced from Uniprot.org