Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit monoclonal antibody anti-Recombinant-T-Box Brain Protein 1 is suitable for use in Western Blot research applications. |
Clonality : | Monoclonal |
Clone ID : | RM2H34 |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide |
Purification: | Protein A/G purified from cell culture supernatant |
Dilution Range: | WB: 1:1000-1:2000 |
Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Gene Symbol: | TBR1 |
Gene ID: | 10716 |
Uniprot ID: | TBR1_HUMAN |
Function | Transcriptional repressor involved in multiple aspects of cortical development, including neuronal migration, laminar and areal identity, and axonal projection. As transcriptional repressor of FEZF2, it blocks the formation of the corticospinal (CS) tract from layer 6 projection neurons, thereby restricting the origin of CS axons specifically to layer 5 neurons. |
Protein Name | T-Box Brain Protein 1T-Brain-1Tbr-1Tes-56 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-T-Box Brain Protein 1 antibodyAnti-T-Brain-1 antibodyAnti-Tbr-1 antibodyAnti-Tes-56 antibodyAnti-TBR1 antibody |
Information sourced from Uniprot.org