| Host: |
Rabbit |
| Applications: |
IF/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : |
Rabbit monoclonal antibody anti-Recombinant-Netrin-1 is suitable for use in Immunofluorescence and Western Blot research applications. |
| Clonality : |
Monoclonal |
| Clone ID : |
RM1G56 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.01M PBS |
| Purification: |
Protein A/G purified from cell culture supernatant |
| Dilution Range: |
IF: 1:50-1:200 |
| Storage Instruction: |
Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Function | Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion. Involved in dorsal root ganglion axon projection towards the spinal cord. It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis. |
| Protein Name | Netrin-1Epididymis Tissue Protein Li 131p |
| Database Links | Reactome: R-HSA-373752Reactome: R-HSA-376172Reactome: R-HSA-418885Reactome: R-HSA-418886Reactome: R-HSA-418890Reactome: R-HSA-428542 |
| Cellular Localisation | SecretedCytoplasmMainly Secreted |
| Alternative Antibody Names | Anti-Netrin-1 antibodyAnti-Epididymis Tissue Protein Li 131p antibodyAnti-NTN1 antibodyAnti-NTN1L antibody |
Information sourced from Uniprot.org
