| Host: | Rabbit |
| Applications: | IF/IHC/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal antibody anti-Recombinant-Dihydrofolate Reductase is suitable for use in Immunofluorescence, Immunohistochemistry and Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | RM1H10 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.01M PBS |
| Purification: | Protein A/G purified from cell culture supernatant |
| Dilution Range: | IF: 1:50-1:200 |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Function | Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFR2. |
| Protein Name | Dihydrofolate Reductase |
| Database Links | Reactome: R-HSA-1474151Reactome: R-HSA-196757Reactome: R-HSA-69205 |
| Cellular Localisation | MitochondrionCytoplasm |
| Alternative Antibody Names | Anti-Dihydrofolate Reductase antibodyAnti-DHFR antibody |
Information sourced from Uniprot.org
