Anti-Recombinant-CAV3 antibody [RM1Z48] (STJA0024923)

SKU:
STJA0024923
£309.50 - £472.50
Free Shipping
Processing The item has been added

Host: Rabbit
Applications: IHC/IP/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Caveolin-3 is suitable for use in Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM1Z48
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: IHC: 1:100-1:200
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: CAV3
Gene ID: 859
Uniprot ID: CAV3_HUMAN
Post Translational Modifications Sumoylation with SUMO3 by PIAS4 may reduce agonist-induced internalization and desensitization of adrenergic receptor ABRD2.
Function May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae.
Protein Name Caveolin-3
M-Caveolin
Database Links Reactome: R-HSA-445355
Cellular Localisation Golgi Apparatus Membrane
Peripheral Membrane Protein
Cell Membrane
Membrane
Caveola
Sarcolemma
Potential Hairpin-Like Structure In The Membrane
Membrane Protein Of Caveolae
Alternative Antibody Names Anti-Caveolin-3 antibody
Anti-M-Caveolin antibody
Anti-CAV3 antibody

Information sourced from Uniprot.org