Host: | Rabbit |
Applications: | IF/IHC/WB |
Reactivity: | Human/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit monoclonal antibody anti-Recombinant-Atp-Binding Cassette Sub-Family F Member 1 is suitable for use in Immunofluorescence, Immunohistochemistry and Western Blot research applications. |
Clonality : | Monoclonal |
Clone ID : | RM2J23 |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide |
Purification: | Protein A/G purified from cell culture supernatant |
Dilution Range: | IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000 |
Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Gene Symbol: | ABCF1 |
Gene ID: | 23 |
Uniprot ID: | ABCF1_HUMAN |
Post Translational Modifications | Isoform 2 is phosphorylated at phosphoserine and phosphothreonine. Isoform 2 phosphorylation on Ser-109 and Ser-140 by CK2 inhibits association of EIF2 with ribosomes. |
Function | Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis. |
Protein Name | Atp-Binding Cassette Sub-Family F Member 1Atp-Binding Cassette 50Tnf-Alpha-Stimulated Abc Protein |
Database Links | Reactome: R-HSA-382556 |
Cellular Localisation | Isoform 2: CytoplasmNucleusNucleoplasmNucleus Envelope |
Alternative Antibody Names | Anti-Atp-Binding Cassette Sub-Family F Member 1 antibodyAnti-Atp-Binding Cassette 50 antibodyAnti-Tnf-Alpha-Stimulated Abc Protein antibodyAnti-ABCF1 antibodyAnti-ABC50 antibody |
Information sourced from Uniprot.org