| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RDH10 |
| Gene ID: | 157506 |
| Uniprot ID: | RDH10_HUMAN |
| Immunogen Region: | 27-293 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-293 of human RDH10 (NP_742034.1). |
| Immunogen Sequence: | VRPKEKSVAGQVCLITGAGS GLGRLFALEFARRRALLVLW DINTQSNEETAGMVRHIYRD LEAADAAALQAGNGEEEILP HCNLQVFTYTCDVGKRENVY LTAERVRKEVGEVSVLVNNA GVVSGHHLLECPDELIERTM MVNCHAHFWTTKAFLPTMLE INHGHIVTVASSLGLFSTAG VEDYCASKFGVVGFHESLSH ELKAAEKDGIKTTLVCPYLV DTGMFRGCRIRKEIEPFLP |
| Tissue Specificity | Detected in retina, kidney, liver, small intestine, placenta, lung, heart and skeletal muscle. |
| Function | Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol. |
| Protein Name | Retinol Dehydrogenase 10Short Chain Dehydrogenase/Reductase Family 16c Member 4 |
| Database Links | Reactome: R-HSA-2453902Reactome: R-HSA-5365859 |
| Cellular Localisation | Microsome MembraneSingle-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Retinol Dehydrogenase 10 antibodyAnti-Short Chain Dehydrogenase/Reductase Family 16c Member 4 antibodyAnti-RDH10 antibodyAnti-SDR16C4 antibodyAnti-UNQ9375 antibodyAnti-PRO34191 antibody |
Information sourced from Uniprot.org