• Western blot analysis of various lysates using WBSCR16 Rabbit polyclonal antibody (STJ116542) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-RCC1L antibody (1-230) (STJ116542)

SKU:
STJ116542

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-WBSCR16 (1-230) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RCC1L
Gene ID: 81554
Uniprot ID: RCC1L_HUMAN
Immunogen Region: 1-230
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human WBSCR16 (NP_110425.2).
Immunogen Sequence: MALVALVAGARLGRRLSGPG LGRGHWTAAGRSRSRREAAE AEAEVPVVQYVGERAARADR VFVWGFSFSGALGVPSFVVP SSGPGPRAGARPRRRIQPVP YRLELDQKISSAACGYGFTL LSSKTADVTKVWGMGLNKDS QLGFHRSRKDKTRGYEYVLE PSPVSLPLDRPQETRVLQVS CGRAHSLVLTDREGVFSMGN NSYGQCGRKVVENEIYSESH RVHRMQDFDG
Tissue Specificity Ubiquitous.
Function Guanine nucleotide exchange factor (GEF) for mitochondrial dynamin-related GTPase OPA1. Activates OPA1, by exchanging bound GDP for free GTP, and drives OPA1 and MFN1-dependent mitochondrial fusion. Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.
Protein Name Rcc1-Like G Exchanging Factor-Like Protein
Rcc1-Like
Williams-Beuren Syndrome Chromosomal Region 16 Protein
Cellular Localisation Mitochondrion Membrane
Mitochondrion Inner Membrane
Alternative Antibody Names Anti-Rcc1-Like G Exchanging Factor-Like Protein antibody
Anti-Rcc1-Like antibody
Anti-Williams-Beuren Syndrome Chromosomal Region 16 Protein antibody
Anti-RCC1L antibody
Anti-WBSCR16 antibody

Information sourced from Uniprot.org

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