| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PTOV1 (1-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PTOV1 |
| Gene ID: |
53635 |
| Uniprot ID: |
PTOV1_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PTOV1 (NP_001292037.1). |
| Immunogen Sequence: |
MRSPAVPTPARGQLGVAFVL LPPHSEGARVFGALGPIGPS SPGLTLGGLAVSEHRLSNKL LAWSGVLEWQEKRRPYSDST AKLKRTLPCQAYVNQGENLE |
| Tissue Specificity | Expressed in brain, heart, kidney, liver, placenta, skeletal muscle and small intestine. |
| Post Translational Modifications | Ubiquitinated by the CRL2(KLHDC2) complex, which recognizes the diglycine (Gly-Gly) at the C-terminus, leading to its degradation. Ubiquitinated by the CRL2(APPBP2) complex, which recognizes the Arg-Xaa-Xaa-Gly sequence at the C-terminus, leading to its degradation. |
| Function | May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation. |
| Protein Name | Prostate Tumor-Overexpressed Gene 1 ProteinPtov-1Activator Interaction Domain-Containing Protein 2 |
| Cellular Localisation | CytoplasmNucleusCell MembranePerinuclear RegionTranslocates From The Cytoplasm To The Nucleus At The Onset Of S-PhaseAlso Localizes To Lipid Rafts |
| Alternative Antibody Names | Anti-Prostate Tumor-Overexpressed Gene 1 Protein antibodyAnti-Ptov-1 antibodyAnti-Activator Interaction Domain-Containing Protein 2 antibodyAnti-PTOV1 antibodyAnti-ACID2 antibodyAnti-PP642 antibodyAnti-UNQ6127 antibodyAnti-PRO20092 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
