| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-POC1B (299-478) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
POC1B |
| Gene ID: |
282809 |
| Uniprot ID: |
POC1B_HUMAN |
| Immunogen Region: |
299-478 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 299-478 of human POC1B (NP_758440.1). |
| Immunogen Sequence: |
TNFDELHCKGLTKRNLKRLH FDSPPHLLDIYPRTPHPHEE KVETVEINPKLEVIDLQIST PPVMDILSFDSTTTTETSGR TLPDKGEEACGYFLNPSLMS PECLPTTTKKKTEDMSDLPC ESQRSIPLAVTDALEHIMEQ LNVLTQTVSILEQRLTLTED KLKDCLENQQKLFSAVQQKS |
| Tissue Specificity | Expressed in the retina. |
| Post Translational Modifications | Phosphorylated in mitotic cells that may be mediated by CDK1. |
| Function | Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Acts in concert with POC1A to ensure centriole integrity and proper mitotic spindle formation. Required for primary cilia formation, ciliary length and also cell proliferation. Required for retinal integrity. |
| Protein Name | Poc1 Centriolar Protein Homolog BPix1Proteome Of Centriole Protein 1bWd Repeat-Containing Protein 51b |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCentrioleCilium Basal BodySpindle PoleComponent Of Both Mother And Daughter CentriolesLocalizes To The Basal Body And Centriole Adjacent To The Connecting Cilium Of Photoreceptors And In Synapses Of The Outer Plexiform Layer |
| Alternative Antibody Names | Anti-Poc1 Centriolar Protein Homolog B antibodyAnti-Pix1 antibodyAnti-Proteome Of Centriole Protein 1b antibodyAnti-Wd Repeat-Containing Protein 51b antibodyAnti-POC1B antibodyAnti-WDR51B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
