| Host: |
Rabbit |
| Applications: |
IF |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Phospholipase D1 (940-1074) is suitable for use in Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PLD1 |
| Gene ID: |
5337 |
| Uniprot ID: |
PLD1_HUMAN |
| Immunogen Region: |
940-1074 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 940-1074 of human PLD1 (NP_002653.1). |
| Immunogen Sequence: |
VMDGKEYQAGRFARGLRLQC FRVVLGYLDDPSEDIQDPVS DKFFKEVWVSTAARNATIYD KVFRCLPNDEVHNLIQLRDF INKPVLAKEDPIRAEEELKK IRGFLVQFPFYFLSEESLLP SVGTKEAIVPMEVWT |
| Tissue Specificity | Expressed abundantly in the pancreas and heart and at high levels in brain, placenta, spleen, uterus and small intestine. |
| Function | Function as phospholipase selective for phosphatidylcholine. Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic. |
| Protein Name | Phospholipase D1Pld 1Hpld1Choline Phosphatase 1Phosphatidylcholine-Hydrolyzing Phospholipase D1 |
| Database Links | Reactome: R-HSA-1483148Reactome: R-HSA-1483166Reactome: R-HSA-2029485Reactome: R-HSA-6798695Reactome: R-HSA-8980692Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-9013408 |
| Cellular Localisation | CytoplasmPerinuclear RegionEndoplasmic Reticulum MembraneLipid-AnchorCytoplasmic SideGolgi Apparatus MembraneLate Endosome Membrane |
| Alternative Antibody Names | Anti-Phospholipase D1 antibodyAnti-Pld 1 antibodyAnti-Hpld1 antibodyAnti-Choline Phosphatase 1 antibodyAnti-Phosphatidylcholine-Hydrolyzing Phospholipase D1 antibodyAnti-PLD1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
